Repeated application of the CANIVERM has no impact on the origin of resistant strains of helminthes

Prevention against parasitic infection belongs to the basic care for the health state of dogs and cats. In particular the puppies and young dogs require regular application of antihelminthics that eliminates toxocarosis which attacks about 40 % dogs of the age category of up to 1 year.

Although the ankylostoma infection is less frequent, the pathogenic effect in form of hemorrhagic enteritis is serious in particular in young animals. During the course of the life, dogs may encounter other helminthes. Trichuris vulpis is able to negatively impact the health condition of a robust adult dog. The significant clinical symptoms are usually not accompanied with tapeworms, but weight loss, loss of hair quality and disquietude at the secretion of elements are a significant indicator of parasitosis.

The regular application of antihelminithics is essential for cats and we therefore recommend it at least every three months for the free-moving animals. The cats get infected with the ascaris eggs that contaminate the external environment and then normally host the adults of Toxocara cati during the entire lifetime. The significant hunting instinct accomplished with ingurgitation of mice that are commonly infected with larvocysts is the cause of repeated infections with tapeworms and the minor rodents are often the reservoirs of ascaris larvae of the Toxocara tribe which also increases the probability of infection.

The stress laid on efficient measures against parasitoses in dogs and cats is based not only on the effort to protect their health, but also on the risk resulting to humans. Most parasitic helminthes in dogs and cats are zoonotic which is even more important for these animals as they live in very close contact with humans. When selecting a correct antihelminitics, the veterinarians may significantly affect occurrence of larval toxocarosis as well as of the dangerous cystic and alveolar echinococcosis in the human population.

An effort is made so that the antiparasitic preparations act against the ordinary spectrum of parasites which consists of nematodes (tribes of Toxocara, Ancylostoma, Trichuris) and tapeworms (Dipylidium caninum, Taenia spp., genus Echinococcus) in dogs and cats. CANIVERM tbl. ad us vet. contains the active substances of fenbendazol, pyrantel and praziquantel in quantities assuring sufficient effect on helminthes in the digestive tract of dogs and cats. Pyrantel acts against ascaris (genus Toxocara, Toxascaris) and hookworms (genus Ancylostoma, Uncinaria), fenbendazol adds the effect against whipworms (Trichuris vulpis). The synergic effect of pyrantel and fenbendazol eliminates the gastrointestinal nematodes if appropriately applied. Praziquantel acts reliably against all the tapeworms in dogs and cats, and therefore also against echinococuses (Echinococcus granulosus, Echinococcus multilocularis) capable of resisting other anticestodics with sufficient effect against the tapeworms of the Taenia genus.

The composition of the preparation CANIVERM tbl. ad us.vet. guarantees high efficacy against gastrointestinal helminthes in dogs and cats. Killing and elimination of parasites from the digestive tract of the host disable the origin of resistant tribes. The basic prerequisite for resistance is the repeated survival of antiparasitic treatment by a part of parasite population. Such capability gradually becomes hereditary and the new population of parasites inherits the resistance against the evoking substance. The issue of resistance is worldwide topical in particular in farming animals (sheet, horses, pigs) in which parasitosis occur regularly with oscillating intensity and antiparasitic substances are often administered. The origin of resistance is also supported by the fact that these animals are mostly kept in larger numbers on a restricted area where they may gradually get infected with resistant tribes of parasites that originated only in individuals at the beginning. The breeding of and care for dogs and cats is individual and the number of parasites, in particular in adult animals, is not at such a level to make the origin of resistant tribes easy. The enhanced stress laid on antiparasitory prevention results rather from the effort to assure good care and, in particular, protection of human health from zoonoses of parasitory origin that may be dangerous to humans even in case of weak infection intensity.

CANIVERM tbl. ad us. vet. belongs to efficient broad-spectrum antiparasitics. Its composition acts reliably against helminthes in the digestive tract of dogs and cats. Repeated application supplemented with control examination of excrements has no impact on the origin of resistant strains of helminthes in dogs and cats.

Prof. MVDr.Vlasta Svobodová, CSc.
Institute of Parasitology
Faculty of Veterinary Medicine
Veterinary University, Brno Czech Republic